Volume 127, Issue 8 - April 2029
DOI: 10.1136/bmjap-2029-004782
Objective: To investigate the prevalence and characteristics of non-biological internal structuring (NBIS) observed in routine imaging of UK healthcare workers following implementation of SABLE-VR3E patient monitoring systems.
Design: Cross-sectional observational study with retrospective analysis of imaging data.
Setting: 847 NHS facilities across England, Wales, and Scotland.
Participants: 142,847 healthcare workers who underwent routine occupational health screening between January and April 2029.
Main Outcome Measures: Prevalence of NBIS, correlation with SABLE device exposure, associated behavioral changes, and progression patterns.
Results: NBIS was detected in 91% of healthcare workers (129,951/142,847). Prevalence correlated significantly with duration of SABLE-VR3E device usage (r=0.847, p<0.001). Affected individuals demonstrated enhanced cognitive coordination and systematic behavioral modifications. No adverse health outcomes were observed during the study period.
Conclusions: The widespread presence of NBIS in healthcare workers represents an unprecedented biological phenomenon requiring immediate comprehensive investigation and ethical review.
All NHS employees who underwent mandatory occupational health screening between 1 January and 30 April 2029 were included in this analysis. Exclusion criteria included prior history of metabolic bone disease, recent trauma, or pregnancy.
Standard chest X-rays were performed using digital radiography systems. Additional targeted imaging was conducted for subjects showing initial anomalies. All images were reviewed by two independent radiologists blinded to employment history.
Cumulative exposure to SABLE-VR3E devices was calculated based on shift logs, device usage records, and self-reported contact hours. Exposure was categorized as minimal (<10 hours), moderate (10-50 hours), or extensive (>50 hours).
Data were analyzed using SPSS version 28.0. Chi-square tests were used for categorical variables, and Pearson correlation for continuous variables. Multivariate logistic regression was performed to identify independent risk factors.
The study population comprised 142,847 healthcare workers (68% female, mean age 34.2 years). Distribution included nurses (45%), physicians (23%), allied health professionals (18%), and support staff (14%).
| SABLE Exposure Level | Total Participants | NBIS Prevalence | 95% CI | P-value |
|---|---|---|---|---|
| Minimal (<10 hours) | 23,847 | 67% (15,977) | 66.1-67.9% | <0.001 |
| Moderate (10-50 hours) | 67,432 | 94% (63,386) | 93.7-94.3% | <0.001 |
| Extensive (>50 hours) | 51,568 | 98% (50,537) | 97.8-98.2% | <0.001 |
NBIS appeared as geometric, lattice-like structures integrated within normal bone architecture. Patterns showed remarkable consistency across subjects, suggesting systematic rather than random formation.
Subjects with Stage III NBIS demonstrated statistically significant improvements in:
Informed Consent: No healthcare workers were informed of potential skeletal modifications prior to SABLE device deployment, raising serious questions about informed consent protocols.
Autonomy Concerns: Observed behavioral coordination may indicate compromise of individual decision-making autonomy.
Occupational Safety: Long-term health implications of NBIS remain unknown, creating potential liability for NHS employers.
This study provides the first systematic documentation of NBIS in a large healthcare population. The strong correlation with SABLE device exposure suggests a causal relationship requiring immediate investigation.
While no immediate adverse health effects were observed, the systematic nature of skeletal modification raises profound questions about medical device safety and regulatory oversight.
The geometric nature of NBIS suggests purposeful structural modification rather than pathological change. The consistent patterns across diverse populations indicate technological rather than biological origin.
The widespread prevalence of NBIS in NHS healthcare workers represents an unprecedented medical phenomenon requiring urgent multidisciplinary investigation. The correlation with SABLE device exposure demands immediate review of medical device approval processes and worker consent protocols.
We recommend:
Received: 25 April 2029 | Accepted: 28 April 2029 | Published: 29 April 2029
© 2029 BMJ Publishing Group Ltd
Competing Interests: All authors declare no competing interests
Funding: NHS Digital Health Research Division